{"id":10606,"date":"2025-09-22T17:19:38","date_gmt":"2025-09-22T15:19:38","guid":{"rendered":"https:\/\/cebio-med.com\/?page_id=10606"},"modified":"2025-11-13T11:53:29","modified_gmt":"2025-11-13T10:53:29","slug":"forschungsprojekte-fuer-aerzte-labore-und-forschungspartner","status":"publish","type":"page","link":"https:\/\/cebio-med.de\/en\/forschungsprojekte\/forschungsprojekte-fuer-aerzte-labore-und-forschungspartner\/","title":{"rendered":"Research Projects \u2013 For Physicians, Laboratories and Research Partners"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"10606\" class=\"elementor elementor-10606\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7f65848 e-flex e-con-boxed e-con e-parent\" data-id=\"7f65848\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-977f2f7 elementor-widget elementor-widget-heading\" data-id=\"977f2f7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Research Projects \u2013 Advancing Knowledge Together<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5d81b57 elementor-widget elementor-widget-text-editor\" data-id=\"5d81b57\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p class=\"translation-block\">The development of diagnostic standards begins with research \u2013 and this is precisely where CEBIO is active.\nTogether with academic institutions, laboratories, clinics, and industry partners, we carry out scientifically grounded and practice-relevant projects that make molecular diagnostics more reliable, comparable, and compliant with regulatory standards.<\/p><p class=\"translation-block\">Our focus areas include key topics such as liquid biopsy, protein analytics, cfDNA reference materials, and the analytical validation of molecular assays.\nOur projects are characterized by methodological depth, structured study designs, biological relevance, and a consistent transfer of results into clinical and diagnostic application.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5785ddd elementor-widget elementor-widget-heading\" data-id=\"5785ddd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Our Research Focus Areas<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d6d7ef6 elementor-widget elementor-widget-text-editor\" data-id=\"d6d7ef6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li class=\"translation-block\"><b>Liquid Biopsy Research<\/b>\nOptimization of pre-analytical processes, molecular assays, and bioinformatics workflows for highly sensitive and reproducible analysis of circulating tumor DNA.<\/li><li class=\"translation-block\"><b>Method Evaluation &amp; Quality Assurance<\/b>\nStatistical assessment of diagnostic procedures in the context of feasibility analyses, validation studies, and quality assurance \u2013 aligned with IVDR requirements and clinical application.<\/li><li class=\"translation-block\"><b>Translational Clinical Biomarker Studies<\/b>\nImplementation of translational biomarker studies within randomized controlled trials, including pre-analytically standardized sample collection and biobanking, high-quality laboratory analyses, and statistical evaluation with validated final reports \u2013 a complete biomarker study service from a single source.<\/li><li class=\"translation-block\"><b>Development of Reference Materials<\/b>\nWe produce cell-based, biologically authentic cfDNA materials ideally suited for test development, method validation, and quality assurance. Our approach follows internationally established standards to ensure high comparability and reproducibility.<\/li><li class=\"translation-block\"><b>Interlaboratory Comparison Studies<\/b>\nDesign and evaluation of interlaboratory studies to assess method robustness, detection limits, and interlaboratory variance \u2013 often based on standardized cfDNA samples.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-889a9da elementor-widget elementor-widget-heading\" data-id=\"889a9da\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Scientifically Visible \u2013 Internationally Connected<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3dbe64b elementor-widget elementor-widget-text-editor\" data-id=\"3dbe64b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p class=\"translation-block\">The results of our research are regularly published in scientific journals and professional articles \u2013 for example, on the analytical validation of cfDNA NGS tests, evaluation of reference samples in proficiency testings, standardization of diagnostic workflows in liquid biopsy, and translational biomarker studies.<\/p><p>CEBIO has contributed as a co-author or methodological partner to numerous national and international publications in areas such as:<\/p><ul><li>cfDNA characterization and reference material validation<\/li><li>Clinical studies on liquid biopsy testing in solid tumors<\/li><li>Clinical evaluation of multiple biomarkers in translational studies<\/li><li>Multicenter NGS ring trials<\/li><li>Sensitivity and specificity analyses of molecular assays<\/li><li>Quality assurance in interdisciplinary diagnostic projects<\/li><\/ul><p class=\"translation-block\">These activities highlight our mission: to develop <b>scientifically robust, regulatory-compliant, and clinically applicable diagnostic solutions.<\/b><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e394238 e-flex e-con-boxed e-con e-parent\" data-id=\"e394238\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-8d32b02 e-con-full e-flex e-con e-child\" data-id=\"8d32b02\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-39f5811 elementor-widget elementor-widget-heading\" data-id=\"39f5811\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Why CEBIO?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-541b0c4 elementor-widget elementor-widget-text-editor\" data-id=\"541b0c4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tCEBIO stands for methodological excellence, project continuity, and collaborative research.\nOur team combines expertise in study design, biostatistics, analytical validation, and laboratory practice \u2013 supported by a strong network in clinical research and industry.\nFrom the initial study concept to implementation and publication, we accompany research projects with a clear focus on reproducibility, data quality, and practical applicability.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8783c70 e-con-full e-flex e-con e-child\" data-id=\"8783c70\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-281db4d elementor-widget elementor-widget-heading\" data-id=\"281db4d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">In Short:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fa69c9a elementor-widget elementor-widget-text-editor\" data-id=\"fa69c9a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>CEBIO designs, supports, and analyzes research projects at the interface of molecular diagnostics, quality standards, and clinical practice.<br \/>With a special focus on liquid biopsy, reference materials, and interlaboratory comparison studies, we deliver reliable data, establish new standards, and create the foundation for modern, reproducible, and future-proof diagnostics.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3ba9564 elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-global elementor-global-10579 elementor-widget-icon-list\" data-id=\"3ba9564\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li 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(0)89-208027-104<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Forschungsprojekte \u2013 Gemeinsam Wissen voranbringen Praxisnah. Interdisziplin\u00e4r. Zielorientiert.Die Entwicklung diagnostischer Standards beginnt in der Forschung \u2013 und genau dort ist CEBIO aktiv. Gemeinsam mit akademischen Institutionen, Laboren, Kliniken und Industriepartnern realisieren wir praxisrelevante, wissenschaftlich fundierte Projekte, die die molekulare Diagnostik sicherer, vergleichbarer und regulatorisch belastbarer machen. Im Fokus stehen aktuelle Schl\u00fcsselthemen wie Liquid Biopsy, Proteinanalytik, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":11008,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-10606","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/cebio-med.de\/en\/wp-json\/wp\/v2\/pages\/10606","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cebio-med.de\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/cebio-med.de\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/cebio-med.de\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cebio-med.de\/en\/wp-json\/wp\/v2\/comments?post=10606"}],"version-history":[{"count":10,"href":"https:\/\/cebio-med.de\/en\/wp-json\/wp\/v2\/pages\/10606\/revisions"}],"predecessor-version":[{"id":11294,"href":"https:\/\/cebio-med.de\/en\/wp-json\/wp\/v2\/pages\/10606\/revisions\/11294"}],"up":[{"embeddable":true,"href":"https:\/\/cebio-med.de\/en\/wp-json\/wp\/v2\/pages\/11008"}],"wp:attachment":[{"href":"https:\/\/cebio-med.de\/en\/wp-json\/wp\/v2\/media?parent=10606"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}