{"id":10596,"date":"2025-09-22T17:00:53","date_gmt":"2025-09-22T15:00:53","guid":{"rendered":"https:\/\/cebio-med.com\/?page_id=10596"},"modified":"2025-11-21T11:04:58","modified_gmt":"2025-11-21T10:04:58","slug":"liquid-biopsy-fuer-mediziner","status":"publish","type":"page","link":"https:\/\/cebio-med.de\/en\/liquid-biopsy\/liquid-biopsy-fuer-mediziner\/","title":{"rendered":"Liquid Biopsy for Physicians"},"content":{"rendered":"
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Liquid Biopsy \u2013 Molecular Tumor Diagnostics from a Blood Sample<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Minimally invasive. Sensitive. Precise.\u00a0
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Liquid biopsy is a modern diagnostic method to assess molecular tumor characteristics on tumor-derived cell-free DNA (ctDNA) circulating in the blood plasma of the patients. Though only a small portion of all DNA in the bloodstream originates from the tumor, it can be detected up to a ratio of 1:1000 to 1:10000 DNA molecules by highly sensitive methods. If no tumor tissue is available for molecular analyses or quick treatment decision is required, liquid biopsy can be used for molecular profiling \u2013 only by a minimally invasive, simple blood draw.\u00a0\u00a0<\/p>

The molecular tumor characterization is required as \u201ccompanion diagnostics\u201d for many targeted therapies. To date, the role of liquid biopsy is investigated for stratification of immunotherapies, too. Large studies demonstrate promising results for postoperative ctDNA assessments for the detection of minimal residual disease and the stratification of adjuvant therapies. Further, liquid biopsy bears great potential for the surveillance of the course of disease during or after systemic therapies: The response to therapy, the early detection of tumor recurrence and the qualification of a patient for a rechallenge therapy becomes measurable by repeated, minimal-invasive tests.<\/p>

Liquid biopsy enables an increasingly personalized tumor diagnostic and therapy and is a valuable, complementary approach to molecular tissue diagnostics. Therefore, highly sensitive and qualitative, diagnostic procedures are needed that fulfil the requirements of the Federal Chamber of Physicians (RiliB\u00c4K) for Liquid Biopsy labs.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Clinical Benefits for Patients<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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